Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14481089 | 0.80 | CPB2 (0.47) | CPB2CCR1CCR5CCR8KDM4E | |
| SCHEMBL17632169 | 0.79 | KDM4E (0.50) | CPB2LOXL2CCR1CCR5CCR8 | |
| SCHEMBL30513290 | 0.79 | KDM4E (0.50) | CPB2LOXL2CCR1CCR5CCR8 | |
| SCHEMBL21425513 | 0.78 | UHRF1 (0.47) | CPB2CCR1CCR5CCR8KDM4E | |
| SCHEMBL30030741 | 0.78 | UHRF1 (0.47) | CPB2CCR1CCR5CCR8KDM4E | |
| SCHEMBL14551585 | 0.76 | CPB2 (0.43) | CPB2KDM4EMEN1KMT2AGRIN1 | |
| SCHEMBL30083563 | 0.76 | CPB2 (0.53) | CPB2CPB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14646909 | 0.72 | KDM4E (0.55) | CPB2KDM4EMEN1KMT2ACPB1 | |
| SCHEMBL7833391 | 0.72 | PLAU (0.58) | CPB2CCR1CCR5CCR8KDM4E | |
| SCHEMBL318010 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2548872-A1 | CYCLOPROPANECARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-23 | — | — | EP | disclosed |