SCHEMBL14647126

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647265	0.91	PARP1 (0.55)	ALDH1A1MEN1KMT2AMAPTHPGD
	SCHEMBL14647123	0.90	PARP1 (0.49)	ALDH1A1MEN1KMT2AMAPTHTT
	SCHEMBL14647216	0.88	NPC1 (0.51)	ALDH1A1MEN1KMT2AMAPTHPGD
	SCHEMBL15703252	0.83	BRD4 (0.46)	ALDH1A1MAPTPARP1BRD4
	SCHEMBL14647112	0.82	PARP1 (0.46)	CYP1A2KDM4EPARP1
	SCHEMBL14647263	0.82	PARP1 (0.52)	ALDH1A1MEN1KMT2AMAPTHPGD
	SCHEMBL15721658	0.78	PARP1 (0.46)	CYP1A2PARP1
	SCHEMBL14647122	0.78	PARP1 (0.66)	ALDH1A1MEN1KMT2AHPGDCYP1A2
	SCHEMBL29893389	0.78	PARP1 (0.50)	ALDH1A1MEN1KMT2AMAPTCYP1A2
	SCHEMBL14647150	0.76	PARP1 (0.55)	ALDH1A1MEN1KMT2AHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.