SCHEMBL14647265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647126	0.91	ALDH1A1 (0.50)	PARP1GAAALDH1A1LMNASMN1; SMN2
	SCHEMBL14647123	0.81	PARP1 (0.49)	PARP1ALDH1A1LMNAHTTMAPK1
	SCHEMBL14647216	0.80	NPC1 (0.51)	ALDH1A1SMN1; SMN2MAPTHPGDKDM4E
	SCHEMBL14647263	0.78	PARP1 (0.52)	PARP1ALDH1A1LMNAHTTMAPT
	SCHEMBL15703252	0.77	BRD4 (0.46)	PARP1ALDH1A1MAPTPOLB
	SCHEMBL14647112	0.76	PARP1 (0.46)	PARP1PRKACAGSK3BDYRK1AKDM4E
	SCHEMBL15721658	0.75	PARP1 (0.46)	PARP1PRKACAGSK3BDYRK1ACYP1A2
	SCHEMBL14647122	0.74	PARP1 (0.66)	PARP1ALDH1A1LMNASMN1; SMN2USP2
	SCHEMBL29893389	0.74	PARP1 (0.50)	PARP1GAAALDH1A1HTTMAPT
	SCHEMBL14647121	0.74	PARP1 (0.48)	PARP1ALDH1A1LMNASMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.