SCHEMBL14647162

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647150	0.93	PARP1 (0.55)	PARP1ALDH1A1LMNASMN1; SMN2MEN1
	SCHEMBL14647155	0.91	—	—
	SCHEMBL14647149	0.86	MAPT (0.55)	ALDH1A1LMNASMN1; SMN2TSHRMAPK1
	SCHEMBL14647220	0.85	TP53 (0.47)	PARP1TP53MAPT
	SCHEMBL14647167	0.82	PARP1 (0.65)	PARP1ALDH1A1KDM4E
	SCHEMBL14647128	0.82	PARP1 (0.51)	PARP1ALDH1A1LMNAMEN1TSHR
	SCHEMBL14647212	0.81	PARP1 (0.61)	PARP1MEN1TSHRKMT2AHPGD
	SCHEMBL14647175	0.80	MGLL (0.49)	PARP1ALDH1A1SMN1; SMN2MAPTHSD17B10
	SCHEMBL14647181	0.80	PARP1 (0.56)	PARP1KMT2A
	SCHEMBL14647161	0.79	MGLL (0.52)	PARP1ALDH1A1LMNASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.