SCHEMBL14647175

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647267	0.87	KDM4E (0.53)	ALDH1A1PARP1ALOX15SMN1; SMN2HSD17B10
	SCHEMBL14647149	0.85	MAPT (0.55)	MGLLALDH1A1USP2MAPTALOX15
	SCHEMBL14647161	0.81	MGLL (0.52)	MGLLALDH1A1PARP1USP2MAPT
	SCHEMBL14647231	0.80	PARP1 (0.49)	ALDH1A1PARP1MAPT
	SCHEMBL14647162	0.80	GPR183 (0.48)	MGLLALDH1A1PARP1MAPTSMN1; SMN2
	SCHEMBL14647121	0.80	PARP1 (0.48)	MGLLNAMPTALDH1A1PARP1SMN1; SMN2
	SCHEMBL14647128	0.80	PARP1 (0.51)	MGLLALDH1A1PARP1HSD17B10
	SCHEMBL14647270	0.79	MGLL (0.46)	MGLLNAMPTALDH1A1PARP1MAPT
	SCHEMBL14647212	0.79	PARP1 (0.61)	PARP1
	SCHEMBL14647163	0.79	SLC6A7 (0.53)	MGLLSPRPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.