Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12172333 | 0.87 | AMY1A (0.45) | ADORA3AMY1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12155330 | 0.84 | AMY1A (0.43) | AMY1AGPR35KDM4EMAPTRXFP1 | |
| SCHEMBL10171244 | 0.84 | ALDH1A1 (0.47) | ADORA3AMY1ANPC1SMN1; SMN2MTNR1B | |
| SCHEMBL13392772 | 0.80 | HTT (0.54) | ADORA3NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL10171537 | 0.75 | CNR2 (0.39) | AMY1ANPC1RAB9AKMT2AGPR35 | |
| SCHEMBL10217001 | 0.74 | CNR2 (0.38) | AMY1ANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL24195277 | 0.73 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL28238289 | 0.73 | KMT2A (0.53) | ADORA3NPC1RAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL14340498 | 0.73 | TP53 (0.56) | NPC1RAB9ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL10171539 | 0.73 | CNR2 (0.55) | ADORA3AMY1AKMT2AGPR35KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342200-B1 | Compounds which selectively modulate the cb2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2013-01-23 | — | — | EP | disclosed |