Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.30 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691057 | 0.82 | CNR2 (0.44) | CNR2PMP22SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14647116 | 0.79 | — | — | |
| SCHEMBL12824338 | 0.74 | CNR2 (0.46) | CNR2 | |
| SCHEMBL1691139 | 0.74 | MMP8 (0.42) | CNR2PMP22 | |
| SCHEMBL12824344 | 0.73 | CNR2 (0.36) | CNR2 | |
| SCHEMBL21839147 | 0.72 | CNR2 (0.33) | CNR2 | |
| SCHEMBL10171155 | 0.70 | CNR2 (0.35) | CNR2 | |
| SCHEMBL12155293 | 0.70 | CNR2 (0.35) | CNR2 | |
| SCHEMBL5651155 | 0.70 | — | — | |
| SCHEMBL469446 | 0.69 | CNR2 (0.44) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342200-B1 | Compounds which selectively modulate the cb2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2013-01-23 | — | — | EP | disclosed |