Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.35 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30509807 | 1.00 | PKM (0.36) | PKMKMT2AMEN1LMNAPER2 | |
| SCHEMBL4301170 | 0.94 | PKM (0.41) | PKMKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL18665525 | 0.94 | PKM (0.41) | PKMKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4287801 | 0.94 | PKM (0.41) | PKMKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7561464 | 0.82 | — | — | |
| SCHEMBL13486887 | 0.80 | — | — | |
| SCHEMBL153432 | 0.80 | — | — | |
| SCHEMBL13486886 | 0.80 | — | — | |
| SCHEMBL4770390 | 0.79 | ALDH1A1 (0.36) | PKMLMNAALDH1A1SMN1; SMN2NR2F2 | |
| SCHEMBL5490567 | 0.79 | HPGD (0.38) | PKMKMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342200-B1 | Compounds which selectively modulate the cb2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2013-01-23 | — | — | EP | disclosed |