Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14647663 | 1.00 | GPR35 (0.46) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL1156982 | 0.83 | GPR35 (0.53) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL1156975 | 0.83 | GPR35 (0.53) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL9948836 | 0.83 | GPR35 (0.53) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL1157293 | 0.82 | GPR35 (0.55) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL1363005 | 0.81 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL1156653 | 0.81 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL12409090 | 0.81 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL12409103 | 0.81 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1LIPGALOX5 | |
| SCHEMBL1364625 | 0.81 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1LIPGALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140131628-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| US-20140131628-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| US-20140131628-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| WO-2013007334-A2 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |