Sugi Predict

Sugi Predict / Compounds / SCHEMBL1156975

SCHEMBL1156975

SCHEMBL1156975

CCCCCCCCCCc1csc2c1sc1c(CCCCCCCCCC)csc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR35 Q9HC97 6/20 0.53
▸ LIPG Q9Y5X9 1/20 0.39
▸ TYR P14679 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ CYP3A4 P08684 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALOX5 P09917 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ CYSLTR2 Q9NS75 2/20 0.36
▸ CYSLTR1 Q9Y271 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ ESR1 P03372 2/20 0.34
▸ ADRA2A P08913 2/20 0.34
▸ ADORA3 P0DMS8 2/20 0.34
▸ TACR2 P21452 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1156982 1.00 GPR35 (0.53) GPR35LIPGTYRTP53CYP3A4
SCHEMBL9948836 1.00 GPR35 (0.53) GPR35LIPGTYRTP53CYP3A4
SCHEMBL12409103 0.98 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL12409090 0.98 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1156657 0.98 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1364625 0.98 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1156653 0.98 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1363005 0.98 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1157293 0.91 GPR35 (0.55) GPR35LIPGTYRTP53CYP3A4
SCHEMBL12060960 0.90 GPR35 (0.46) GPR35LIPGTYRTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2308882-B1 Fused thiophenes and uses thereof CORNING INC (US) 2018-06-13 — — EP disclosed
EP-2773646-B1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2016-06-15 — — EP disclosed
EP-2129678-B1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2015-05-27 — — EP disclosed
US-8846855-B2 Conjugated fused thiophenes, methods of making conjugated fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2014-09-30 — — US disclosed
EP-1799688-B1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2013-06-19 — — EP disclosed
US-20130109821-A1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED 2013-05-02 — — US disclosed
US-20130085256-A1 FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED 2013-04-04 — — US disclosed
US-8389669-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2013-03-05 — — US disclosed
US-8349998-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2013-01-08 — — US disclosed
EP-2308882-A1 Fused thiophenes and uses thereof Corning Incorporated (US) 2011-04-13 — — EP disclosed
US-20110082278-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2011-04-07 — — US disclosed
US-7893191-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2011-02-22 — — US disclosed
US-20110040042-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2011-02-17 — — US disclosed
US-7838623-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2010-11-23 — — US disclosed
US-7705108-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2010-04-27 — — US disclosed
US-20100010237-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2010-01-14 — — US disclosed
US-20070265418-A1 Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof CORNING INCORPORATED 2007-11-15 — — US disclosed
US-20070161776-A1 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED 2007-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110040042-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4429/4885LIPG 4076/4885TYR 91/4885
US-20130109821-A1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF TST, TPMT, TPR GPR35 4231/4885LIPG 2887/4885TYR 56/4885
US-20130085256-A1 FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TPR GPR35 4480/4885LIPG 2963/4885TYR 77/4885
US-20110082278-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4429/4885LIPG 4076/4885TYR 91/4885
US-20100010237-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4520/4885LIPG 3969/4885TYR 93/4885
US-20070265418-A1 Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof TPMT, TST, TYMP GPR35 4429/4885LIPG 4076/4885TYR 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.