SCHEMBL14648592

SCHEMBL14648592

Cc1c(N=O)cc(N=O)cc1N=O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP3A4 P08684 2/20 0.31
TRPA1 O75762 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13334327 0.80 ACHE (0.35) ALDH1A1TSHRCYP3A4LMNAHTT
SCHEMBL28051432 0.79 MEN1 (0.40) ALDH1A1MAPK1HSD17B10LMNAHTT
SCHEMBL28191051 0.77 ALDH1A1 (0.35) ALDH1A1LMNAHTT
SCHEMBL28051550 0.77
SCHEMBL14470991 0.74 ALDH1A1 (0.33) ALDH1A1TP53TSHRMAPK1HIF1A
SCHEMBL28174120 0.74 BRD4 (0.38) ALDH1A1TP53TSHRMAPK1HIF1A
SCHEMBL22914760 0.74 CYP3A4 (0.34) CYP3A4TRPA1LMNAHTT
SCHEMBL6050007 0.72 CYP3A4 (0.50) ALDH1A1TP53TSHRMAPK1HIF1A
SCHEMBL17366351 0.71 ALDH1A1 (0.36) ALDH1A1TP53TSHRMAPK1HIF1A
SCHEMBL24541493 0.71 ALDH1A1 (0.35) ALDH1A1TP53TSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013010882-A2 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-01-24 WO disclosed