Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 2/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14396802 | 0.80 | PDE4D (0.35) | PDE4DPDE4BMEN1KMT2ACYP1A2 | |
| SCHEMBL19121052 | 0.79 | NUDT1 (0.45) | CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL18418865 | 0.78 | PDE4D (0.35) | PDE4DLMNAPDE4BMEN1KMT2A | |
| SCHEMBL12806591 | 0.78 | PDE4D (0.37) | PDE4DLMNAPDE4BMEN1KMT2A | |
| SCHEMBL18376454 | 0.78 | SMN1; SMN2 (0.36) | PDE4DLMNAPDE4BCYP1A2CYP2C19 | |
| SCHEMBL15884466 | 0.78 | NPC1 (0.44) | PDE4DLMNAPDE4BMEN1KMT2A | |
| SCHEMBL19121529 | 0.77 | NPSR1 (0.35) | LMNACYP1A2CYP2C19SMN1; SMN2LRRK2 | |
| SCHEMBL26828650 | 0.77 | MAT2A (0.33) | S1PR2CYP1A2CYP2C19 | |
| SCHEMBL26754925 | 0.77 | SCN9A (0.35) | LMNAMEN1KMT2ACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL27087821 | 0.76 | PDE4D (0.35) | PDE4DPDE4BMEN1KMT2APDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217879-A1 | PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |
| WO-2013010758-A1 | NEMATOCIDE N- CYCLOPROPYL - SULFONYLAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |