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SCHEMBL14650613

SCHEMBL14650613

CC(COCC(C)N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(N1CCN(C)CC1)C5=O)N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(N1CCN(C)CC1)C5=O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.38
▸ STAT3 P40763 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ NPC1 O15118 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.33
▸ RAD52 P43351 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14650695 0.90 TERT (0.33) TERTSTAT3HIF1ANPC1TDP1
SCHEMBL14650538 0.84 TERT (0.31) TERT
SCHEMBL13929490 0.80 NPC1 (0.36) TERTNPC1TDP1
SCHEMBL17692575 0.79 TERT (0.40) TERTSTAT3HIF1ATDP1
SCHEMBL11948123 0.77 NPC1 (0.34) TERTHIF1ANPC1TDP1
SCHEMBL14650588 0.76 STAT3 (0.51) TERTSTAT3HIF1ANPC1TDP1
SCHEMBL14650633 0.75 KMT2A (0.42) TERTSTAT3HIF1ATDP1
SCHEMBL14650634 0.74 TDP1 (0.43) TERTNPC1TDP1
SCHEMBL14650601 0.74 STAT3 (0.49) TERTSTAT3HIF1ANPC1
SCHEMBL14650636 0.73 TERT (0.49) TERTSTAT3HIF1ARAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9051468-B2 Dyes for polymer coloration, their preparation and their use CLARIANT INTERNATIONAL LTD (CH) 2015-06-09 — — US disclosed
US-20130019415-A1 DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2013-01-24 — — US disclosed
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