Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650705 | 0.91 | TERT (0.43) | TERTSTAT3HIF1AHTR1ADRD2 | |
| SCHEMBL14650540 | 0.86 | TERT (0.40) | TERTSTAT3HIF1AHTR1ADRD2 | |
| SCHEMBL30574144 | 0.85 | TERT (0.65) | TERTSTAT3HIF1AHTR1ADRD2 | |
| SCHEMBL14650588 | 0.82 | STAT3 (0.51) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650601 | 0.80 | STAT3 (0.49) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650671 | 0.78 | STAT3 (0.46) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650615 | 0.77 | KDM4E (0.51) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650611 | 0.77 | CYP1B1 (0.52) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650630 | 0.75 | CYP1B1 (0.49) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650587 | 0.74 | STAT3 (0.43) | TERTSTAT3HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |