SCHEMBL14651302

SCHEMBL14651302

COC12CC3CC(CO)(C1)CC(C(=O)Oc1ccc(OC(=O)C45CC6CC(OC)(CC(OC)(C6)C4)C5)cc1)(C3)C2

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
XBP1 P17861 1/20 0.41
HSD11B1 P28845 1/20 0.35
HSD11B2 P80365 1/20 0.35
TP53 P04637 2/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 1/20 0.34
ATM Q13315 1/20 0.33
TOP2A P11388 1/20 0.33
CNR2 P34972 1/20 0.33
P2RX2 Q9UBL9 1/20 0.31
SCN9A Q15858 1/20 0.31
P2RX7 Q99572 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14654299 0.88 GAA (0.50) GAAMAPTXBP1HSD11B1HSD11B2
SCHEMBL15779842 0.80
SCHEMBL10172076 0.77
SCHEMBL10219727 0.74 SCN9A (0.31) SCN9A
SCHEMBL680294 0.70 ALDH1A1 (0.32) ALDH1A1
SCHEMBL20659894 0.68 LMNA (0.49) GAAHSD11B1LMNAALDH1A1MEN1
SCHEMBL4032638 0.67 MEN1 (0.40) GAAMAPTPOLBALDH1A1MEN1
SCHEMBL15780101 0.67 NPSR1 (0.35) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL5082277 0.66 MAPT (0.53) GAAMAPTXBP1TP53LMNA
SCHEMBL686305 0.66 NPSR1 (0.34) MAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765336-B2 Electrophotographic photoreceptor and manufacturing method therefor FUJI ELECTRIC CO., LTD. (JP) 2014-07-01 US disclosed
US-20130022904-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND MANUFACTURING METHOD THEREFORE FUJI ELECTRIC CO., LTD. (JP) 2013-01-24 US disclosed