Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 6/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717018 | 0.84 | MEN1 (0.60) | CLTCAPEX1MEN1KMT2ALPAR2 | |
| SCHEMBL14652569 | 0.81 | CYP2C9 (0.55) | CLTCCYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL4234742 | 0.78 | CLTC (0.78) | CLTCAPEX1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7848586 | 0.77 | ERCC1 (0.62) | CLTCMEN1KMT2AALDH1A1CA12 | |
| N-Phthaloylanthranilic Acid SCHEMBL29549628 | 0.75 | APEX1 (0.71) | APEX1LMNAALDH1A1GAAL3MBTL1 | |
| N-Phthaloylanthranilic Acid SCHEMBL481284 | 0.75 | APEX1 (0.71) | APEX1LMNAALDH1A1GAAL3MBTL1 | |
| SCHEMBL6389919 | 0.72 | HSD17B10 (0.49) | APEX1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL28869011 | 0.72 | CA12 (0.50) | CLTCMEN1KMT2AALDH1A1GAA | |
| SCHEMBL3827398 | 0.72 | ALDH1A1 (0.55) | CLTCMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL5750370 | 0.72 | MEN1 (0.59) | MEN1KMT2ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |