Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267867 | 0.93 | MAPT (0.77) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL10378226 | 0.90 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL31110328 | 0.89 | MAPT (0.69) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5267339 | 0.85 | GSTP1 (0.47) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5271242 | 0.85 | FTO (0.60) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL31689739 | 0.84 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL17863886 | 0.83 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1HTT | |
| Fluorescein Diacetate SCHEMBL31658971 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1HTT | |
| Fluorescein Diacetate SCHEMBL1028369 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1HTT | |
| Fluorescein Diacetate SCHEMBL29353816 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013012687-A2 | COMBINATIONS OF FLUORPHORES AND PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2013-01-24 | — | — | WO | disclosed |