SCHEMBL5267339

SCHEMBL5267339

CC(=O)OCOC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(N(C)C)cc2Oc2c1ccc1cc(OC(C)=O)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.47
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
USP2 O75604 1/20 0.47
HPGD P15428 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 2/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FTO Q9C0B1 4/20 0.33
KCNH2 Q12809 2/20 0.33
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
NR4A1 P22736 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10378226 0.89 MEN1 (0.52) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL14653307 0.85 MAPT (0.66) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL29672382 0.84 MAPT (0.67) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL31689739 0.82 MAPT (0.45) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL13620618 0.79 MAPT (0.53) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL5267867 0.78 MAPT (0.77) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL10376806 0.76 FTO (0.45) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL13146300 0.76 GSTP1 (0.47) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL8230429 0.75 MEN1 (0.46) GSTP1ALDH1A1MEN1KMT2AMAPT
SCHEMBL31110328 0.74 MAPT (0.69) GSTP1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0731664-B1 SENSOR WITH IMPROVED DRIFT STABILITY TERUMO CARDIOVASCULAR SYS (US) 2002-02-27 EP claimed
US-5403746-A Aqueous first phase comprising pH sensitive indicator in buffer solution dispersed in hydrophobic second phase permeable to analyte and impermeable to ionized hydrogen MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-04 US claimed
US-12042281-B2 Fluorescent nanomaterial sensors and related methods TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) 2024-07-23 US disclosed
US-20210015410-A1 FLUORESCENT NANOMATERIAL SENSORS AND RELATED METHODS TERUMO CARDIOVASCULAR SYSTEMS CORPORATION 2021-01-21 US disclosed
EP-0963567-B1 ASSEMBLY FOR RETAINING OPTICAL COMPONENTS TERUMO CARDIOVASCULAR SYS (US) 2007-10-10 EP disclosed
EP-0993266-B1 CASSETTE FOR MEASURING PARAMETERS OF BLOOD TERUMO CARDIOVASCULAR SYS (US) 2005-10-19 EP disclosed
EP-0994669-B1 BLOOD PARAMETER MEASUREMENT DEVICE TERUMO CARDIOVASCULAR SYS (US) 2004-09-29 EP disclosed
EP-0971621-B1 CASSETTE FOR TONOMETRIC CALIBRATION TERUMO CARDIOVASCULAR SYS (US) 2004-09-15 EP disclosed
EP-0731664-B1 SENSOR WITH IMPROVED DRIFT STABILITY TERUMO CARDIOVASCULAR SYS (US) 2002-02-27 EP disclosed
US-6217828-B1 FOR GASES TERUMO CARDIOVASCULAR SYSTEMS CORPORATION 2001-04-17 US disclosed
US-6208880-B1 Blood parameter measurement device TERUMO CARDIOVASCULAR SYSTEMS CORPORATION 2001-03-27 US disclosed
EP-1054257-A2 Emulsion for robust sensing of gases Terumo Cardiovascular Systems Corporation (US) 2000-11-22 EP disclosed
US-6101406-A Cassette for measuring parameters of blood TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) 2000-08-08 US disclosed
EP-0971621-A1 CASSETTE FOR TONOMETRIC CALIBRATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-01-19 EP disclosed
US-6009339-A Blood parameter measurement device TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) 1999-12-28 US disclosed
US-5997818-A FOR CALIBRATING SENSORS OF A BLOOD PARAMETER MEASUREMENT SYSTEM. MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-12-07 US disclosed
WO-1998037800-A1 CASSETTE FOR TONOMETRIC CALIBRATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-09-03 WO disclosed
US-5607645-A Sensor with improved drift stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-04 US disclosed
US-5403746-A Aqueous first phase comprising pH sensitive indicator in buffer solution dispersed in hydrophobic second phase permeable to analyte and impermeable to ionized hydrogen MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-04 US disclosed
US-4945171-A FLUORESCENT DYES MOLECULAR PROBES, INC. (US) 1990-07-31 US disclosed