Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15699138 | 0.88 | DYRK1A (0.76) | DYRK1APIM1 | |
| SCHEMBL102421 | 0.86 | DYRK1A (0.91) | DYRK1APIM1 | |
| SCHEMBL29436156 | 0.85 | DYRK1A (0.73) | DYRK1APIM1 | |
| SCHEMBL102330 | 0.85 | DYRK1A (0.73) | DYRK1APIM1 | |
| SCHEMBL26745373 | 0.84 | DYRK1A (1.00) | DYRK1APIM1 | |
| Sulfuric Acid SCHEMBL30631762 | 0.84 | DYRK1A (0.53) | DYRK1APIM1 | |
| SCHEMBL19987042 | 0.82 | PIM1 (0.76) | DYRK1APIM1 | |
| SCHEMBL24333076 | 0.81 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL13867672 | 0.81 | PIM1 (0.77) | DYRK1APIM1 | |
| SCHEMBL14653658 | 0.81 | DYRK1A (0.74) | DYRK1APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812387-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | Sumitomo Dainippon Pharma Oncology, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3409278-B1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | TOLERO PHARMACEUTICALS INC (US) | 2020-09-16 | — | — | EP | disclosed |
| EP-2734205-B1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | TOLERO PHARMACEUTICALS INC (US) | 2018-03-21 | — | — | EP | disclosed |
| WO-2013013188-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | TOLERO PHARMACEUTICALS, INC. (US) | 2013-01-24 | — | — | WO | disclosed |