Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 12/20 | 0.76 |
| ▸ | PIM1 | P11309 | 7/20 | 0.69 |
| ▸ | FYN | P06241 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102421 | 0.89 | DYRK1A (0.91) | DYRK1APIM1FYN | |
| SCHEMBL14653586 | 0.88 | DYRK1A (0.73) | DYRK1APIM1 | |
| SCHEMBL102330 | 0.88 | DYRK1A (0.73) | DYRK1APIM1 | |
| SCHEMBL29436156 | 0.88 | DYRK1A (0.73) | DYRK1APIM1 | |
| SCHEMBL26745373 | 0.86 | DYRK1A (1.00) | DYRK1APIM1FYN | |
| SCHEMBL19987042 | 0.84 | PIM1 (0.76) | DYRK1APIM1FYN | |
| SCHEMBL24333076 | 0.83 | DYRK1A (1.00) | DYRK1AFYN | |
| SCHEMBL13867672 | 0.83 | PIM1 (0.77) | DYRK1APIM1 | |
| SCHEMBL14373133 | 0.83 | FYN (0.73) | DYRK1AFYN | |
| SCHEMBL24333204 | 0.83 | DYRK1A (1.00) | DYRK1APIM1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140135323-A1 | OXO-SUBSTITUTED IMIDAZO[1,2B]PYRIDAZINES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135323-A1 | OXO-SUBSTITUTED IMIDAZO[1,2B]PYRIDAZINES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | CDK2, CDK1, MAP4K2 | DYRK1A 445/4885PIM1 712/4885FYN 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.