Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856065 | 0.68 | — | — | |
| SCHEMBL4671656 | 0.67 | NISCH (0.41) | KDM4ECYP1A2CYP2D6HSD17B10ALOX15 | |
| Cyclomethyltryptophan SCHEMBL416558 | 0.65 | KDM4E (0.71) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL7889282 | 0.65 | KDM4E (0.71) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL416557 | 0.65 | KDM4E (0.71) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL29535380 | 0.65 | KDM4E (0.71) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL28419799 | 0.64 | KDM4E (0.69) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL10642614 | 0.64 | KDM4E (0.69) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14654367 | 0.64 | CYP2A6 (0.33) | ALDH1A1 | |
| Cyclomethyltryptophan SCHEMBL30798742 | 0.63 | KDM4E (0.44) | GRIA2EGLN1KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616571-A2 | Lysine containing peptides for treatment of heart disease | Ardana Bioscience Limited (GB) | 2006-01-18 | — | — | EP | disclosed |
| EP-1131083-B1 | USE OF GROWTH HORMONE RELEASING COMPOUNDS AND THEIR ANTAGONISTS FOR THE TREATMENT OF TUMORS | ARDANA BIOSCIENCE LTD (GB) | 2004-01-21 | — | — | EP | disclosed |
| EP-1131083-A1 | TREATMENT OF TUMORS BY ADMINISTRATION OF GROWTH HORMONE RELEASING COMPOUNDS AND THEIR ANTAGONISTS | ASTA Medica Aktiengesellschaft (DE) | 2001-09-12 | — | — | EP | disclosed |
| US-6124263-A | Treatment of tumors by administration of growth hormone releasing compounds and their antagonists | ASTA MEDICA AG (DE) | 2000-09-26 | — | — | US | disclosed |
| WO-2000029011-A1 | TREATMENT OF TUMORS BY ADMINISTRATION OF GROWTH HORMONE RELEASING COMPOUNDS AND THEIR ANTAGONISTS | ZENTARIS AG (DE) | 2000-05-25 | — | — | WO | disclosed |
| US-6025471-A | EXHIBIT BINDING TO CARDIAC TISSUE AND NORMALIZE CARDIAC PRESSURE AFTER ADMINISTRATION, AS WELL AS DIAGNOSTIC AND THERAPEUTIC PROPERTIES FOR CERTAIN NEOPLASTIC TISSUES; PREFERABLY HAVE AT LEAST ONE LYSINE UNIT AND AT LEAST ONE | ARDANA BIOSCIENCE LIMITED (GB) | 2000-02-15 | — | — | US | disclosed |
| US-5932548-A | ANTIISCHEMIC AGENTS USING PEPTIDES | ARDANA BIOSCIENCE LIMITED (GB) | 1999-08-03 | — | — | US | disclosed |