SCHEMBL1465437

SCHEMBL1465437

C=CCCCCCCCCCCF

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ABCC4 O15439 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 5/20 0.43
TRPA1 O75762 3/20 0.41
LPAR3 Q9UBY5 2/20 0.38
LMNA P02545 2/20 0.38
LPAR2 Q9HBW0 1/20 0.38
TDP1 Q9NUW8 2/20 0.34
USP2 O75604 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28999156 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL28999186 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL16933997 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL28999163 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL812439 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL2136014 1.00
SCHEMBL16933837 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL7880094 1.00
SCHEMBL7905219 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL28999273 1.00 TSHR (0.52) TSHRABCC4MAPTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063345-B Phosphonic acid group monomer and preparation method thereof 中国石油化工股份有限公司 2024-08-06 CN disclosed
CN-116063626-B Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
CN-116064016-B Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof 中国石油化工股份有限公司 2024-04-05 CN disclosed
CN-116063345-A Phosphonic acid group monomer and preparation method thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
CN-116063626-A Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
CN-116064016-A Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
US-8173110-B2 Pre-shave preparation with enhanced lubricity COMBE INCORPORATED (US) 2012-05-08 US disclosed
US-20110070178-A1 Pre-Shave Preparation With Enhanced Lubricity JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2011-03-24 US disclosed
US-20090053158-A1 Pre-Shave Preparation With Enhanced Lubricity COMBE INCORPORATED 2009-02-26 US disclosed
EP-0460393-A1 Resin composition for primer use and primer composition employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 1991-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090053158-A1 Pre-Shave Preparation With Enhanced Lubricity SYVN1, VCL, DSG1 TSHR 3864/4885ABCC4 4543/4885MAPT 1238/4885
US-20110070178-A1 Pre-Shave Preparation With Enhanced Lubricity SYVN1, VCL, DSG1 TSHR 3864/4885ABCC4 4543/4885MAPT 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.