Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191795 | 0.92 | LMNA (0.44) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28852289 | 0.92 | TRPA1 (0.48) | LMNAPPARGTRPA1DDAH1GAPDH | |
| SCHEMBL27644434 | 0.92 | TRPA1 (0.48) | LMNAPPARGTRPA1DDAH1GAPDH | |
| SCHEMBL28131157 | 0.92 | TRPA1 (0.48) | LMNAPPARGTRPA1DDAH1GAPDH | |
| SCHEMBL8434341 | 0.92 | TRPA1 (0.48) | LMNAPPARGTRPA1DDAH1GAPDH | |
| SCHEMBL8437504 | 0.92 | TRPA1 (0.48) | LMNAPPARGTRPA1DDAH1GAPDH | |
| SCHEMBL27828958 | 0.92 | TRPA1 (0.48) | LMNAPPARGTRPA1DDAH1GAPDH | |
| SCHEMBL29013305 | 0.88 | LMNA (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29013339 | 0.88 | LMNA (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29013338 | 0.88 | LMNA (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778712-B1 | 2-PROPYNYL ADENOSINE ANALOGS WITH MODIFIED 5'-RIBOSE GROUPS HAVING A2A AGONIST ACTIVITY | Univ Virginia Patent Found (US) | 2013-01-30 | — | — | EP | disclosed |