SCHEMBL14656755

SCHEMBL14656755

O=Cc1sc(-c2cccs2)c(-c2cccs2)c1C=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.44
ERN1 O75460 6/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TYMP P19971 1/20 0.34
ALDH1A1 P00352 4/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
KDM4E B2RXH2 3/20 0.33
LMNA P02545 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
NFKB1 P19838 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15400093 0.82 DPP4 (0.42) DPP4ERN1MEN1KMT2ATYMP
SCHEMBL4319170 0.73 MEN1 (0.47) DPP4MEN1KMT2ATYMPALDH1A1
SCHEMBL2524601 0.72 MEN1 (0.38) DPP4MEN1KMT2ATYMPALDH1A1
SCHEMBL11829475 0.70 ERN1 (0.43) DPP4ERN1MEN1KMT2AALDH1A1
SCHEMBL10551506 0.69 ERN1 (0.45) DPP4ERN1MEN1KMT2ATYMP
SCHEMBL246872 0.69 ERN1 (0.45) DPP4ERN1MEN1KMT2AALDH1A1
SCHEMBL9414143 0.69 DPP4 (0.42) DPP4ERN1MEN1KMT2ATYMP
SCHEMBL12191851 0.67 DPP4 (0.41) DPP4ERN1MEN1KMT2AALDH1A1
SCHEMBL7135870 0.66 MAPT (0.52) DPP4MEN1KMT2ATYMPALDH1A1
SCHEMBL9231804 0.66 ERN1 (0.49) DPP4ERN1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2559720-A1 CROSSLINKED COMPOSITION Daicel Corporation (JP) 2013-02-20 EP disclosed
US-20130026458-A1 CROSSLINKABLE COMPOSITION DAICEL CORPORATION (JP) 2013-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026458-A1 CROSSLINKABLE COMPOSITION DDC, ODC1, SRM DPP4 4713/4885ERN1 1867/4885MEN1 1744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.