Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.48 |
| ▸ | CTSA | P10619 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14717207 | 0.92 | PIN1 (0.52) | PIN1CTSAFFAR2HPGDSMAPT | |
| SCHEMBL14662578 | 0.91 | PIN1 (0.46) | PIN1CTSAFFAR2PTPN1HPGDS | |
| SCHEMBL14662703 | 0.90 | PIN1 (0.52) | PIN1CTSAMMEHPGDSMAPT | |
| SCHEMBL14717964 | 0.88 | CTSA (0.54) | CTSAMMEFFAR2HPGDSMAPT | |
| SCHEMBL14662316 | 0.87 | PIN1 (0.51) | PIN1MMEHPGDSMAPTTDP1 | |
| SCHEMBL14661878 | 0.85 | PANK3 (0.52) | PIN1CTSA | |
| SCHEMBL14661926 | 0.82 | PIN1 (0.67) | PIN1HPGDSMAPTTDP1NPY1R | |
| SCHEMBL14661956 | 0.82 | TLR7 (0.48) | PIN1CTSA | |
| SCHEMBL14662374 | 0.82 | PIN1 (0.53) | PIN1CTSAHPGDS | |
| SCHEMBL14717228 | 0.82 | TLR7 (0.56) | CTSAMMEFFAR2HPGDSTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736891-A1 | SUBSTITUTED 3 - (THIAZOLE - 4 - CARBONYL) - OR 3 - (THIAZOLE - 2 - CARBONYL) AMINOPROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-06-04 | — | — | EP | claimed |
| WO-2013014205-A1 | SUBSTITUTED 3 - (THIAZOLE - 4 - CARBONYL) - OR 3 - (THIAZOLE - 2 - CARBONYL) AMINOPROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2013-01-31 | — | — | WO | claimed |
| EP-2736891-A1 | SUBSTITUTED 3 - (THIAZOLE - 4 - CARBONYL) - OR 3 - (THIAZOLE - 2 - CARBONYL) AMINOPROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-06-04 | — | — | EP | disclosed |
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |
| WO-2013014205-A1 | SUBSTITUTED 3 - (THIAZOLE - 4 - CARBONYL) - OR 3 - (THIAZOLE - 2 - CARBONYL) AMINOPROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2013-01-31 | — | — | WO | disclosed |