Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | DUT | P33316 | 5/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | ENTPD2 | Q9Y5L3 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14140653 | 1.00 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL13389961 | 1.00 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL13389805 | 1.00 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL14664284 | 0.91 | DUT (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL14665202 | 0.90 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL14665217 | 0.84 | DUT (0.37) | DUTP2RY2P2RY4P2RY14 | |
| SCHEMBL14665220 | 0.84 | DUT (0.37) | DUTP2RY2P2RY4P2RY14 | |
| SCHEMBL14664270 | 0.83 | SLC28A1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL13390018 | 0.83 | DUT (0.43) | DUTP2RY2P2RY4P2RY6 | |
| SCHEMBL14664287 | 0.82 | RNASE1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361988-B2 | Nucleoside and nucleotide analogues with quaternary carbon centers and methods of use | INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) | 2013-01-29 | — | — | US | disclosed |