Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067043 | 0.83 | POLB (0.31) | LMNA | |
| SCHEMBL25704255 | 0.77 | GSK3A (0.42) | GSK3AGSK3BOPRM1OPRD1OPRK1 | |
| SCHEMBL30395097 | 0.77 | GSK3A (0.42) | GSK3AGSK3BOPRM1OPRD1OPRK1 | |
| SCHEMBL10067009 | 0.77 | HDAC3 (0.36) | ALDH1A1LMNA | |
| SCHEMBL25683883 | 0.74 | GSK3A (0.42) | GSK3AGSK3BALDH1A1BLMCYP1A2 | |
| SCHEMBL25679992 | 0.74 | GSK3A (0.42) | GSK3AGSK3BALDH1A1BLMCYP1A2 | |
| SCHEMBL25680048 | 0.73 | GSK3A (0.41) | GSK3AGSK3BOPRM1OPRD1OPRK1 | |
| SCHEMBL19795400 | 0.72 | GSK3A (0.44) | GSK3AGSK3BALDH1A1BLMCYP1A2 | |
| SCHEMBL10018581 | 0.70 | MGLL (0.38) | OPRM1OPRD1OPRK1ALDH1A1BLM | |
| SCHEMBL3665093 | 0.70 | GSK3A (0.52) | GSK3AGSK3BALDH1A1BLMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361442-B2 | Oxime conjugates and methods for their formation and use | THE GENERAL HOSPITAL CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |