SCHEMBL146689

SCHEMBL146689

O=C(OF)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL18784490 0.98 TSHR (0.41) TSHRKDM4ETDP1USP2MAPT
SCHEMBL714348 0.93 TSHR (0.41) TSHRKDM4ETDP1USP2MAPT
SCHEMBL713038 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL720226 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL403954 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL713217 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL716379 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
Hydrochloric Acid SCHEMBL18784439 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL715943 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL712408 0.91 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365751-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2025-07-22 US claimed
CN-120189948-A Method for solid phase synthesis of nickel phyllosilicate catalyst under solvent-free condition 山东科技大学 2025-06-24 CN claimed
CN-118461044-A MOF hydrophobic microenvironment regulation ruthenium nanoparticle catalyst and preparation method and application thereof 中国科学院合肥物质科学研究院 2024-08-09 CN claimed
CN-111848832-B Application of fluorine-containing compound modified cationic polymer as drug carrier and preparation method thereof 苏州大学 2024-02-20 CN claimed
CN-114409887-B Fluorinated end group amphiphilic polymer, preparation method and application thereof 浙江大学杭州国际科创中心 2023-09-01 CN claimed
CN-111848831-B Application of fluorine-containing compound modified cationic polymer in preparation of vaccine medicine 苏州大学 2023-06-13 CN claimed
CN-114409887-A Fluorinated terminal group amphiphilic polymer, and preparation method and application thereof 浙江大学杭州国际科创中心 2022-04-29 CN claimed
US-11315713-B2 Superconductor and method for manufacturing same KABUSHIKI KAISHA TOSHIBA (JP) 2022-04-26 US claimed
US-20220034852-A1 MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES WATERS TECHNOLOGIES CORPORATION 2022-02-03 US claimed
US-11092574-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2021-08-17 US claimed
CN-113117096-A NCAM mimic peptide modified pH sensitive gene bionic delivery system and application thereof 复旦大学 2021-07-16 CN claimed
CN-111024831-A Method for separating moxifloxacin hydrochloride and impurities thereof by high performance liquid chromatography 江苏正大丰海制药有限公司 2020-04-17 CN claimed
US-20200027634-A1 SUPERCONDUCTOR AND METHOD FOR MANUFACTURING SAME KABUSHIKI KAISHA TOSHIBA (JP) 2020-01-23 US claimed
CN-110656395-A Breathable sweat-absorbent antibacterial fragrant textile fabric 深圳市大毛牛新材料科技有限公司 2020-01-07 CN claimed
EP-3276637-B1 SUPERCONDUCTOR AND METHOD FOR MANUFACTURING SAME TOSHIBA KK (JP) 2019-06-19 EP claimed
EP-3276637-A1 SUPERCONDUCTOR AND METHOD FOR MANUFACTURING SAME Kabushiki Kaisha Toshiba (JP) 2018-01-31 EP claimed
US-20180012689-A1 SUPERCONDUCTOR AND METHOD FOR MANUFACTURING SAME KABUSHIKI KAISHA TOSHIBA (JP) 2018-01-11 US claimed
US-20150316515-A1 MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES WATERS TECHNOLOGIES CORPORATION 2015-11-05 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 TSHR 4082/4885KDM4E 1567/4885TDP1 1182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.