SCHEMBL714348

SCHEMBL714348

O=C(OF)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714357 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL712408 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL715943 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
Hydrochloric Acid SCHEMBL18784439 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL713217 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL715364 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL720226 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL713038 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL716379 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2
SCHEMBL403954 0.98 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12006439-B2 Optical member, optical device and coating liquid CANON KABUSHIKI KAISHA (JP) 2024-06-11 US claimed
EP-4095162-A1 APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER Soochow University (CN) 2022-11-30 EP claimed
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD SOOCHOW UNIVERSITY (CN) 2022-09-01 US claimed
WO-2022142152-A1 CONTENT MEASUREMENT METHOD FOR CLINDAMYCIN PHOSPHATE VAGINAL TABLET 海南海神同洲制药有限公司 2022-07-07 WO claimed
CN-112684056-B Content determination method of clindamycin phosphate vaginal tablets 海南海神同洲制药有限公司 2022-04-29 CN claimed
CN-108878260-B Low-friction fluorine-containing onion carbon film and method for directly preparing same on silicon substrate 江苏大学 2021-09-10 CN claimed
CN-110715999-B High-throughput screening method for 200 chemical risk substances in toy 中国检验检疫科学研究院 2021-08-20 CN claimed
WO-2021147585-A1 USE OF CHITOSAN MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER AND PREPARATION METHOD THEREFOR 苏州大学 2021-07-29 WO claimed
WO-2021147598-A1 APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER 苏州大学 2021-07-29 WO claimed
CN-113121792-A UV-cured fluorine-modified waterborne epoxy resin and preparation method thereof 上海三桐材料科技有限公司 2021-07-16 CN claimed
CN-110556509-A Method for performing surface protection and passivation treatment on metallic lithium cathode by using fluorine-containing organic matter, product and application NANJING UNIVERSITY OF TECHNOLOGY 2019-12-10 CN claimed
US-9828458-B2 Silica particles coated with β-cyclodextrin for the removal of emerging contaminants from wastewater Temple University—Of the Commonwealth System of Higher Education (US) 2017-11-28 US claimed
US-9687816-B2 Method of regeneration of beta-cyclodextrin based adsorbent-coated silica with ozone Temple University—Of the Commonwealth System of Higher Education (US) 2017-06-27 US claimed
US-20160367967-A1 Method of Regeneration of Beta-Cyclodextrin Based Adsorbent-Coated Silica With Ozone Temple University--of the Commonwealth System of Higher Education 2016-12-22 US claimed
EP-3036198-A1 WATER TREATMENT FOR REMOVAL OF ENDOCRINE DISRUPTING CHEMICALS Temple University Of The Commonwealth System Of Higher Education (US) 2016-06-29 EP claimed
WO-2015131066-A1 REGENERATING BETA-CYCLODEXTRIN BASED ADSORBENT-COATED SILICA WITH OZONE TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2015-09-03 WO claimed
EP-2768666-A1 SILICA PARTICLES COATED WITH BETA-CYCLODEXTRIN FOR THE REMOVAL OF EMERGING CONTAMINANTS FROM WASTEWATER Temple University Of The Commonwealth System Of Higher Education (US) 2014-08-27 EP claimed
US-20140231352-A1 SILICA PARTICLES COATED WITH BETA-CYCLODEXTRIN FOR THE REMOVAL OF EMERGING CONTAMINANTS FROM WASTEWATER TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2014-08-21 US claimed
WO-2013059285-A1 SILICA PARTICLES COATED WITH BETA-CYCLODEXTRIN FOR THE REMOVAL OF EMERGING CONTAMINANTS FROM WASTEWATER TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2013-04-25 WO claimed
US-6383274-B1 Ink jet ink compositions and printing processes XEROX CORPORATION 2002-05-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD F12, SLCO4C1, SLC7A1 TSHR 111/4885KDM4E 989/4885TDP1 4195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.