SCHEMBL14669246

SCHEMBL14669246

CCCCCCCC/C=C\CCCCCCCC(=O)OCCCOP(=O)(O)OCCC

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ P2RY10 O00398 10/20 0.73
▸ GPR34 Q9UPC5 5/20 0.73
▸ LPAR1 Q92633 5/20 0.57
▸ ENPP2 Q13822 3/20 0.57
▸ LPAR4 Q99677 2/20 0.57
▸ LPAR5 Q9H1C0 2/20 0.57
▸ LPAR2 Q9HBW0 2/20 0.57
▸ LPAR3 Q9UBY5 2/20 0.57
▸ CES2 O00748 1/20 0.57
▸ LPAR6 P43657 1/20 0.57
▸ TRPV1 Q8NER1 1/20 0.57
▸ GPR174 Q9BXC1 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21778318 0.94 P2RY10 (0.72) P2RY10GPR34LPAR1ENPP2LPAR4
SCHEMBL23188400 0.94 P2RY10 (0.72) P2RY10GPR34LPAR1ENPP2LPAR4
SCHEMBL14669247 0.92 P2RY10 (0.71) P2RY10GPR34LPAR1ENPP2LPAR4
SCHEMBL4804427 0.92 P2RY10 (0.70) P2RY10GPR34LPAR1
SCHEMBL14240582 0.91 P2RY10 (0.72) P2RY10GPR34LPAR1GPR174
SCHEMBL23188432 0.90 P2RY10 (0.68) P2RY10GPR34LPAR1ENPP2LPAR4
SCHEMBL14669245 0.90 P2RY10 (0.68) P2RY10GPR34LPAR1ENPP2LPAR4
SCHEMBL21778295 0.90 P2RY10 (0.67) P2RY10GPR34LPAR1ENPP2LPAR4
SCHEMBL12075311 0.89 LPAR3 (0.68) P2RY10GPR34LPAR1ENPP2LPAR4
SCHEMBL23188413 0.89 P2RY10 (0.67) P2RY10GPR34LPAR1ENPP2LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210108198-A1 APPLICATION OF COMPOUND OR TRADITIONAL CHINESE MEDICINE EXTRACT IN PREPARATION OF NUCLEIC ACID DELIVERY AGENT AND RELATED PRODUCTS THEREOF BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2021-04-15 — — US disclosed
EP-2718261-B1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORP (JP) 2016-02-24 — — EP disclosed
US-20130026051-A1 BIOSENSOR UNIVERSITY OF LEEDS (GB) 2013-01-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210108198-A1 APPLICATION OF COMPOUND OR TRADITIONAL CHINESE MEDICINE EXTRACT IN PREPARATION OF NUCLEIC ACID DELIVERY AGENT AND RELATED PRODUCTS THEREOF TRDMT1, HNRNPAB, HNRNPA1 P2RY10 4517/4885GPR34 3580/4885LPAR1 649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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