Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466563 | 0.93 | NOTUM (0.34) | NOTUMPYGLPDK2F2F10 | |
| SCHEMBL3457366 | 0.91 | NOTUM (0.37) | NOTUMPYGLCA1CA2 | |
| SCHEMBL1466504 | 0.89 | PDK2 (0.34) | NOTUMPDK2F2F10PRSS1 | |
| SCHEMBL1858890 | 0.88 | NOTUM (0.39) | NOTUMPYGLCA1CA2 | |
| SCHEMBL738385 | 0.88 | NOTUM (0.36) | NOTUMPYGLCA1CA2 | |
| SCHEMBL1801804 | 0.85 | PDK2 (0.34) | NOTUMPDK2F2F10PRSS1 | |
| SCHEMBL14956129 | 0.85 | NOTUM (0.36) | NOTUMPYGLCA1CA2 | |
| SCHEMBL13692112 | 0.85 | NOTUM (0.36) | NOTUMPYGLF2F10PRSS1 | |
| SCHEMBL1799389 | 0.85 | NPC1 (0.36) | NOTUMPDK2F2F10PRSS1 | |
| SCHEMBL1468195 | 0.85 | KDM4E (0.37) | NOTUMPDK2F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | BAYER CROPSCIENCE AG | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | DDT, PRDX4, CYP4X1 | NOTUM 1692/4885PYGL 2575/4885PDK2 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.