SCHEMBL1801804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1799389	0.93	NPC1 (0.36)	PDK2KDM4ECA1CA2F2
	SCHEMBL1466563	0.92	NOTUM (0.34)	PDK2KDM4ECA1CA2F2
	SCHEMBL1801082	0.92	ACLY (0.33)	KDM4ECA1CA2F2F10
	SCHEMBL1466992	0.91	PDK2 (0.34)	PDK2KDM4ECA1CA2F2
	SCHEMBL1797708	0.91	ACVR1 (0.37)	KDM4ECA1CA2F2F10
	SCHEMBL1796305	0.90	PDK2 (0.34)	PDK2KDM4ECA1CA2F2
	SCHEMBL1798501	0.89	F2 (0.32)	KDM4ECA1CA2F2F10
	SCHEMBL2529138	0.88	PDK2 (0.45)	PDK2KDM4ECA1CA2F2
	SCHEMBL23778641	0.87	KDM4E (0.39)	PDK2KDM4ECA1CA2F2
	SCHEMBL362563	0.87	KDM4E (0.39)	PDK2KDM4ECA1CA2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.