SCHEMBL1467052

SCHEMBL1467052

NC(=O)Oc1ccncc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
KIF11 P52732 1/20 0.50
CYP1A2 P05177 3/20 0.46
CYP2C19 P33261 3/20 0.46
LMNA P02545 2/20 0.46
CYP2C9 P11712 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP19A1 P11511 1/20 0.44
NAPRT Q6XQN6 1/20 0.41
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MPO P05164 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CYP2A6 P11509 1/20 0.40
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630925 0.87 KIF11 (0.62) HSD17B10MEN1KMT2AKIF11CYP1A2
SCHEMBL29260073 0.82 CYP17A1 (0.56) HSD17B10MEN1KMT2AKIF11CYP1A2
SCHEMBL6284986 0.82 KMT2A (0.64) HSD17B10MEN1KMT2AKIF11LMNA
SCHEMBL18727667 0.80 HSD17B10 (0.58) HSD17B10MEN1KMT2ACYP1A2CYP2C19
SCHEMBL23355573 0.78 HSD17B10 (0.56) HSD17B10MEN1KMT2ACYP1A2CYP2C19
SCHEMBL380364 0.78 HSD17B10 (0.56) HSD17B10MEN1KMT2ACYP1A2CYP2C19
Carbamic Acid Phenyl Ester SCHEMBL28650557 0.77 MEN1 (0.53) HSD17B10MEN1KMT2AKIF11LMNA
SCHEMBL27950381 0.76 HSD17B10 (0.54) HSD17B10MEN1KMT2ACYP1A2CYP2C19
SCHEMBL20412354 0.76 HSD17B10 (0.54) HSD17B10MEN1KMT2ACYP1A2CYP2C19
SCHEMBL1467050 0.76 HSD17B10 (0.54) HSD17B10MEN1KMT2ACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084766-A 2-Indolone compound and preparation method thereof 云南大学 2024-05-28 CN claimed
CN-109689664-A The quinoline and azepine quinoline compound that tricyclic heteroaryl as PAR4 inhibitor replaces 百时美施贵宝公司 2019-04-26 CN claimed
CN-103209695-A Azabenzothiazole compounds, compositions and methods of use HOFFMANN LA ROCHE 2013-07-17 CN claimed
EP-0619810-A1 SUBSTITUTED PYRIDIN-4-CARBOXYLIC ACID AMIDES AND THEIR USE FOR PROTECTING PLANTS AGAINST INFECTION BY MICROORGANISMS BAYER AG (DE) 1994-10-19 EP claimed
WO-1993010095-A1 SUBSTITUTED PYRIDIN-4-CARBOXYLIC ACID AMIDES AND THEIR USE FOR PROTECTING PLANTS AGAINST INFECTION BY MICROORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 1993-05-27 WO claimed
EP-0253372-A2 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indoles, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1988-01-20 EP claimed
CN-118084766-A 2-Indolone compound and preparation method thereof 云南大学 2024-05-28 CN disclosed
CN-117015745-A Recording a latent holographic grating and magnifying its dynamic range 元平台技术有限公司 2023-11-07 CN disclosed
CN-116997827-A Spatially varying dynamic range in holographic gratings 元平台技术有限公司 2023-11-03 CN disclosed
CN-109843879-B Benzothiazole derivatives as DYRK1 inhibitors 药物治疗股份有限公司 2023-05-02 CN disclosed
CN-114929705-A MLL1 inhibitor and anticancer agent 诺华公司 2022-08-19 CN disclosed
CN-109689647-A The compound that bicyclic heteroaryl replaces 百时美施贵宝公司 2019-04-26 CN disclosed
CN-109689664-A The quinoline and azepine quinoline compound that tricyclic heteroaryl as PAR4 inhibitor replaces 百时美施贵宝公司 2019-04-26 CN disclosed
EP-0619810-A1 SUBSTITUTED PYRIDIN-4-CARBOXYLIC ACID AMIDES AND THEIR USE FOR PROTECTING PLANTS AGAINST INFECTION BY MICROORGANISMS BAYER AG (DE) 1994-10-19 EP disclosed
EP-0602562-A1 Process for the preparation of phthalocyanine reactive dyes BASF Aktiengesellschaft (DE) 1994-06-22 EP disclosed
WO-1993010095-A1 SUBSTITUTED PYRIDIN-4-CARBOXYLIC ACID AMIDES AND THEIR USE FOR PROTECTING PLANTS AGAINST INFECTION BY MICROORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 1993-05-27 WO disclosed
WO-1993010095-A1 SUBSTITUTED PYRIDIN-4-CARBOXYLIC ACID AMIDES AND THEIR USE FOR PROTECTING PLANTS AGAINST INFECTION BY MICROORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 1993-05-27 WO disclosed
EP-0527441-A2 Water-soluble phthalocyanine dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-17 EP disclosed
EP-0231837-B1 PROCESS FOR THE PREPARATION OF WATER SOLUBLE PHTHALOCYANINE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-02 EP disclosed
EP-0231837-A2 Process for the preparation of water soluble phthalocyanine dyes HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-12 EP disclosed