Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18727667 | 0.80 | HSD17B10 (0.58) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL23355573 | 0.78 | HSD17B10 (0.56) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL380364 | 0.78 | HSD17B10 (0.56) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL55400 | 0.77 | TDP1 (0.52) | HSD17B10CYP19A1ALDH1A1TSHRKDM4E | |
| SCHEMBL5170271 | 0.76 | HSD17B10 (0.54) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL701147 | 0.76 | LMNA (0.58) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL1467052 | 0.76 | HSD17B10 (0.54) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL20412354 | 0.76 | HSD17B10 (0.54) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL27950381 | 0.76 | HSD17B10 (0.54) | HSD17B10CYP19A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL1466982 | 0.76 | KMT2A (0.56) | HSD17B10LMNACYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | BAYER CROPSCIENCE AG | 2011-03-24 | — | — | US | disclosed |
| CN-101970403-A | Insecticidal fused ring aryl compounds | BAYER CROPSCIENCE AG | 2011-02-09 | — | — | CN | disclosed |
| EP-2254863-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009112275-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | DDT, PRDX4, CYP4X1 | HSD17B10 2993/4885CYP19A1 140/4885LMNA 1126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.