SCHEMBL146715

SCHEMBL146715

C=Cc1ccccc1C(Cl)(Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TSHR P16473 4/20 0.39
KCNN4 O15554 2/20 0.34
CYP1A2 P05177 1/20 0.33
KDM4E B2RXH2 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524435 0.79 ALDH1A1 (0.41) ALDH1A1TSHRKCNN4KDM4EHTT
SCHEMBL7633180 0.79 ALDH1A1 (0.56) ALDH1A1TSHRKCNN4
SCHEMBL11724522 0.78 TSHR (0.55) ALDH1A1TSHRKCNN4CYP1A2HTT
SCHEMBL28706855 0.76 ESR1 (0.41) ALDH1A1TSHRKCNN4KDM4E
SCHEMBL4789180 0.76 ALDH1A1 (0.41) ALDH1A1TSHRKCNN4KDM4E
SCHEMBL28831873 0.76 ALDH1A1 (0.39) ALDH1A1TSHRKCNN4KDM4EHTT
SCHEMBL29056471 0.75 ALDH1A1 (0.46) ALDH1A1TSHR
Benzene SCHEMBL11667348 0.72 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL11238521 0.72 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL4238555 0.72 ALDH1A1 (0.43) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120059137-A1 MONODISPERSE CHLOROMETHYLSTYRENE POLYMER AND PRODUCING METHOD THEREOF AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed