SCHEMBL4789180

SCHEMBL4789180

C=Cc1ccccc1C(C)(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.35
TSHR P16473 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
NR3C2 P08235 3/20 0.33
KDM4E B2RXH2 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
ALOX15 P16050 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31
KCNN4 O15554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28706855 0.84 ESR1 (0.41) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL6745721 0.83 ESR1 (0.43) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL14999529 0.81 NFE2L2 (0.36) ALDH1A1ESR1ESR2CYP3A4MAPK1
Benzene SCHEMBL11667348 0.81 ALDH1A1 (0.48) ALDH1A1TSHRTDP1MAPTGAA
SCHEMBL17508181 0.80 KMT2A (0.46) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL28138729 0.80 ESR1 (0.41) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL7524435 0.79 ALDH1A1 (0.41) ALDH1A1MAPK1TSHRKDM4EALOX15
SCHEMBL27805 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTDP1MAPTKMT2A
SCHEMBL29801228 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTDP1MAPTKMT2A
SCHEMBL14959982 0.78 ALDH1A1 (0.31) ALDH1A1ESR1ESR2CYP3A4NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253835-A Method for producing conjugated diene polymer, and conjugated diene polymer, rubber and tire obtained thereby 台橡股份有限公司 2023-06-13 CN disclosed
WO-2008123387-A2 WATER-BASED PAINT COMPOSITIONS AND MULTILAYER COATING FILM FORMING METHOD KANSAI PAINT CO., LTD. (JP) 2008-10-16 WO disclosed