SCHEMBL146732

SCHEMBL146732

O=Cc1ccc(O)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.59
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 1/20 0.56
NPC1 O15118 1/20 0.56
HSP90AA1 P07900 1/20 0.56
RAB9A P51151 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
TRIM24 O15164 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
CTSL P07711 4/20 0.50
CAPN1 P07384 3/20 0.50
CTSB P07858 3/20 0.50
ERN1 O75460 4/20 0.48
HDAC3 O15379 1/20 0.46
EP300 Q09472 1/20 0.46
KAT2B Q92831 1/20 0.46
KAT8 Q9H7Z6 1/20 0.46
NCOR2 Q9Y618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29673385 1.00 IDO1 (0.59) IDO1MEN1KMT2AKDM4ENPC1
SCHEMBL7537816 0.87 IDO1 (0.46) IDO1MEN1KMT2AKDM4ENPC1
SCHEMBL2994301 0.86 ERN1 (0.61) IDO1MEN1KMT2AKDM4ENPC1
SCHEMBL29956391 0.86 ERN1 (0.61) IDO1MEN1KMT2AKDM4ENPC1
SCHEMBL29786760 0.85 KMT2A (0.61) IDO1MEN1KMT2AKDM4ENPC1
SCHEMBL982388 0.85 KMT2A (0.61) IDO1MEN1KMT2AKDM4ENPC1
SCHEMBL7708552 0.81 IDO1 (0.65) IDO1CTSLCAPN1CTSBHDAC3
Formic Acid SCHEMBL27496593 0.80 IDO1 (0.72) IDO1TRIM24TRIM33CTSLCAPN1
SCHEMBL9353776 0.78 APP (0.58) IDO1MEN1KMT2AKDM4ENPC1
Formamide SCHEMBL9732415 0.78 IDO1 (0.48) IDO1MEN1KMT2AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
CN-118731194-A Detection method of alkyl diamine 四川科伦药物研究院有限公司 2024-10-01 CN claimed
CN-118359558-A Hemicyanine dye fluorescent probe for detecting hydrogen sulfite, preparation method thereof, detection method and application thereof in solution and biological system 华北理工大学 2024-07-19 CN claimed
CN-117820252-A Preparation and detection methods of nitroreductase hemicyanine dye fluorescent probes and visual application of nitroreductase hemicyanine dye fluorescent probes in clinical bacterial identification 华北理工大学 2024-04-05 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
EP-4244150-A1 AROMATIC DIOL COMPOUNDS, DIEPOXIDE COMPOUNDS, POLYMERS PREPARED FROM SUCH COMPOUNDS, AND METHODS FOR MAKING THE SAME Swimc LLC (US) 2023-09-20 EP claimed
CN-116438120-A Aromatic diol compound, diepoxide compound, polymer prepared from such compound, and process for producing the same SWIMC有限公司 2023-07-14 CN claimed
WO-2023087503-A1 PREPARATION OF NOVEL ISOPHORONE DERIVATIVES AND USE THEREOF IN FIELDS OF ORGANELLE LABELING AND VISCOSITY DETECTION 苏州大学 2023-05-25 WO claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-08-18 US claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-1235549-A1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-04 EP claimed
EP-1227786-A1 AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE Wella Aktiengesellschaft (DE) 2002-08-07 EP claimed
WO-2001097765-A1 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001097764-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
EP-1143923-A1 AGENT AND METHOD FOR COLOURING FIBRES Wella Aktiengesellschaft (DE) 2001-10-17 EP claimed
WO-2001062219-A1 AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE WELLA AKTIENGESELLSCHAFT (DE) 2001-08-30 WO claimed
WO-2001034106-A1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-17 WO claimed
WO-2001028507-A1 AGENT AND METHOD FOR COLOURING FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2001-04-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, VIM, CDH1 IDO1 3570/4885MEN1 1333/4885KMT2A 172/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO IDO1 51/4885MEN1 3135/4885KMT2A 631/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO IDO1 51/4885MEN1 3135/4885KMT2A 631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.