Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336664 | 0.84 | CYP4F2 (0.49) | CYP3A4ALDH1A1CYP4F2CYP4A11KDM4E | |
| SCHEMBL21178007 | 0.79 | CYP3A4 (0.49) | CYP3A4ALDH1A1KDM4EHSD17B10CA2 | |
| SCHEMBL27767401 | 0.79 | ALDH1A1 (0.55) | CYP3A4ALDH1A1KDM4EHSD17B10IDH1 | |
| SCHEMBL3790510 | 0.78 | ALDH1A1 (0.64) | CYP3A4ALDH1A1CYP4F2CYP4A11KDM4E | |
| SCHEMBL8078817 | 0.76 | CYP3A4 (0.50) | CYP3A4ALDH1A1CA2TSHRGAA | |
| SCHEMBL990642 | 0.76 | ALDH1A1 (0.61) | CYP3A4ALDH1A1CYP4F2CYP4A11KDM4E | |
| SCHEMBL31160231 | 0.76 | ALDH1A1 (0.61) | CYP3A4ALDH1A1CYP4F2CYP4A11KDM4E | |
| SCHEMBL3293016 | 0.75 | ALDH1A1 (0.52) | CYP3A4ALDH1A1KDM4EHSD17B10CA2 | |
| SCHEMBL5936414 | 0.75 | CYP3A4 (0.55) | CYP3A4ALDH1A1KDM4EHSD17B10CA2 | |
| SCHEMBL4655268 | 0.75 | CYP3A4 (0.55) | CYP3A4ALDH1A1KDM4EHSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | BAYER CROPSCIENCE AG | 2011-03-24 | — | — | US | disclosed |
| EP-2254863-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009112275-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | DDT, PRDX4, CYP4X1 | CYP3A4 222/4885ALDH1A1 1268/4885CYP4F2 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.