Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361658 | 0.88 | MAPT (0.65) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL14675887 | 0.86 | MAPT (0.65) | MAPTLMNAL3MBTL1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL9097442 | 0.85 | MAPT (0.61) | MAPTLMNAL3MBTL1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL9097449 | 0.85 | MAPT (0.61) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL13603664 | 0.85 | MAPT (0.61) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL14675442 | 0.83 | MAPT (0.67) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL6902202 | 0.82 | MAPT (0.66) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL6689290 | 0.82 | PDK1 (0.69) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL3609842 | 0.81 | MAPT (0.77) | MAPTLMNAL3MBTL1MAPK1HTT | |
| SCHEMBL6665955 | 0.81 | MAPT (0.64) | MAPTLMNAL3MBTL1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409904-B2 | Compounds and compositions for use in augmentation of glucose | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2016-08-09 | — | — | US | disclosed |
| US-20150025094-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-01-22 | — | — | US | disclosed |
| EP-2739612-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE UPTAKE AND INSULIN SECRETION | Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. (IL) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013018095-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE UPTAKE AND INSULIN SECRETION | YISSUM RESEARCH AND DEVELOPMENT OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2013-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025094-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE | SLC5A2, SLC2A2, SLC2A1 | MAPT 4597/4885LMNA 1819/4885L3MBTL1 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.