Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PPARA | Q07869 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17153802 | 0.93 | PDK1 (0.61) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL6902202 | 0.91 | MAPT (0.66) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL9468354 | 0.91 | MAPT (0.61) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL9467080 | 0.89 | PDK1 (0.57) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL6665955 | 0.89 | MAPT (0.64) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL9468058 | 0.88 | KMT2A (0.64) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL10475190 | 0.88 | ALDH1A1 (0.67) | MAPTLMNAL3MBTL1MAPK1KMT2A | |
| SCHEMBL6691987 | 0.88 | PDK1 (0.66) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL6690610 | 0.88 | PDK1 (0.53) | PDK1MAPTLMNAL3MBTL1MAPK1 | |
| SCHEMBL9468312 | 0.86 | PDK1 (0.53) | PDK1MAPTLMNAL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010283-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2002-01-24 | — | — | US | claimed |
| EP-0854168-A1 | Rubber composition | Bridgestone Corporation (JP) | 1998-07-22 | — | — | EP | claimed |
| EP-2739612-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE UPTAKE AND INSULIN SECRETION | YISSUM RES DEV CO (IL) | 2017-06-21 | — | — | EP | disclosed |
| US-9409904-B2 | Compounds and compositions for use in augmentation of glucose | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2016-08-09 | — | — | US | disclosed |
| US-9409904-B2 | Compounds and compositions for use in augmentation of glucose | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2016-08-09 | — | — | US | disclosed |
| US-9409904-B2 | Compounds and compositions for use in augmentation of glucose | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2016-08-09 | — | — | US | disclosed |
| US-20150287953-A1 | TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | Konica Minolta, Inc. (JP) | 2015-10-08 | — | — | US | disclosed |
| US-20150025094-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-01-22 | — | — | US | disclosed |
| US-20150025094-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-01-22 | — | — | US | disclosed |
| US-20150025094-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-01-22 | — | — | US | disclosed |
| EP-2739612-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE UPTAKE AND INSULIN SECRETION | Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. (IL) | 2014-06-11 | — | — | EP | disclosed |
| US-6186204-B1 | EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0555769-B1 | Process for the preparation of Cephem-Prodrug-esters | HOECHST AG (DE) | 1999-09-15 | — | — | EP | disclosed |
| EP-0890605-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0854168-A1 | Rubber composition | Bridgestone Corporation (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5637721-A | Process for the preparation of cephem prodrug esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5589594-A | AMIDATION OF 7-AMINOCEPH-3-EM-4-CARBOXYLIC ESTER USING AMINOTHIAZOLE OXIME CARBOXYLIC ACID WITH REMOVAL OF PROTECTING GROUP BY ACID HYDROLYSIS AND CLEAVAGE OF DISULFIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-31 | — | — | US | disclosed |
| EP-0555769-A2 | Process for the preparation of Cephem-Prodrug-esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-18 | — | — | EP | disclosed |
| US-4138346-A | ETHOXYLATED PHOSPHATE ESTER WITH A MERCAPTOTHIAZOLE, A DITHIOBIS-THIAZOLE, A SULFIDE, A DISULFIDE OR A SULFONE | BASF WYANDOTTE CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025094-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE | SLC5A2, SLC2A2, SLC2A1 | PDK1 944/4885MAPT 4597/4885LMNA 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.