SCHEMBL14676338

SCHEMBL14676338

CCSc1cccnc1-c1nc2cc(SC(F)(F)F)cnc2n1C

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.34
▸ LMNA P02545 1/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ USP2 O75604 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ ALOX15 P16050 1/20 0.31
▸ HDAC1 Q13547 1/20 0.31
▸ HDAC8 Q9BY41 1/20 0.31
▸ HDAC6 Q9UBN7 1/20 0.31
▸ HDAC5 Q9UQL6 1/20 0.31
▸ PTPN11 Q06124 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431636 1.00 POLB (0.34) POLBLMNARAB9AUSP2SMN1; SMN2
Acetonitrile SCHEMBL15862505 0.95 POLB (0.32) POLBLMNA
SCHEMBL14684581 0.88 LMNA (0.35) POLBLMNARAB9AUSP2SMN1; SMN2
SCHEMBL15868297 0.87 LMNA (0.34) POLBLMNARAB9AUSP2SMN1; SMN2
SCHEMBL10280726 0.85 ALOX5AP (0.35) POLBRAB9ASMN1; SMN2NPC1PKM
SCHEMBL14676724 0.85 POLB (0.48) POLBLMNARAB9AUSP2SMN1; SMN2
SCHEMBL29431603 0.85 POLB (0.48) POLBLMNARAB9AUSP2SMN1; SMN2
SCHEMBL15868283 0.84 POLB (0.40) POLBLMNARAB9AUSP2SMN1; SMN2
SCHEMBL15275097 0.84 AKT1 (0.40) POLBLMNARAB9AUSP2SMN1; SMN2
SCHEMBL14684623 0.84 POLB (0.40) POLBLMNARAB9AUSP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112021322-B Compositions and methods for controlling pests 住友化学株式会社 2022-04-01 — — CN disclosed
CN-112021322-A Compositions and methods for controlling pests 住友化学株式会社 2020-12-04 — — CN disclosed
EP-2952099-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-17 — — EP disclosed
EP-2952097-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
EP-2952100-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-9854805-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
US-9018134-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-28 — — US disclosed
WO-2014119672-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD 住友化学株式会社 (JP) 2014-08-07 — — WO disclosed
WO-2014119674-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD 住友化学株式会社 (JP) 2014-08-07 — — WO disclosed
WO-2014119699-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD 住友化学株式会社 (JP) 2014-08-07 — — WO disclosed
WO-2014119679-A1 PEST-CONTROL METHOD 住友化学株式会社 (JP) 2014-08-07 — — WO disclosed
US-20140194290-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-10 — — US disclosed
US-20140194290-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-10 — — US disclosed
EP-2739624-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2014-06-11 — — EP disclosed
WO-2013018928-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 — — WO disclosed
WO-2013018928-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140194290-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR0B1, NR4A1, NR2C2 POLB 4628/4885LMNA 1994/4885RAB9A 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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