Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | APLNR | P35414 | 2/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.44 |
| ▸ | CALCR | P30988 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677288 | 1.00 | C5AR1 (0.49) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL14677421 | 0.92 | CXCR4 (0.56) | C5AR1CXCR4F2APLNRMC4R | |
| SCHEMBL14677425 | 0.92 | CXCR4 (0.56) | C5AR1CXCR4F2APLNRMC4R | |
| SCHEMBL30997477 | 0.88 | F2 (0.52) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL31683847 | 0.86 | C5AR1 (0.44) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL29473726 | 0.84 | CXCR4 (0.55) | C5AR1CXCR4F2APLNRCALCR | |
| SCHEMBL31290257 | 0.84 | MC4R (0.55) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL30537453 | 0.84 | CXCR4 (0.57) | C5AR1CXCR4F2APLNR | |
| SCHEMBL31598487 | 0.84 | OPRM1 (0.60) | C5AR1CXCR4CTSLCTSSCTSK | |
| SCHEMBL31598478 | 0.84 | OPRM1 (0.60) | C5AR1CXCR4CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034913-B2 | Anti-angiogenic peptides and uses thereof | HEALTH RESEARCH, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20160051623-A1 | ANTI-ANGIOGENIC PEPTIDES AND USES THEREOF | HEALTH RESEARCH, INC. | 2016-02-25 | — | — | US | disclosed |
| US-20140309170-A1 | ANTI-ANGIOGENIC PEPTIDES AND USES THEREOF | HEALTH RESEARCH, INC. (US) | 2014-10-16 | — | — | US | disclosed |
| WO-2013019445-A2 | ANTI-ANGIOGENIC PEPTIDES AND USES THEREOF | HEALTH RESEARCH, INC. (US) | 2013-02-07 | — | — | WO | disclosed |