Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 7/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | APLNR | P35414 | 2/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.49 |
| ▸ | CALCR | P30988 | 3/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.49 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677421 | 1.00 | CXCR4 (0.56) | CXCR4MC4RAPLNRC5AR1F2 | |
| SCHEMBL14677288 | 0.92 | C5AR1 (0.49) | CXCR4MC4RAPLNRC5AR1F2 | |
| SCHEMBL14677292 | 0.92 | C5AR1 (0.49) | CXCR4MC4RAPLNRC5AR1F2 | |
| SCHEMBL30495678 | 0.89 | C5AR1 (0.66) | CXCR4MC4RAPLNRC5AR1 | |
| SCHEMBL29968139 | 0.86 | RAMP3 (0.59) | CXCR4F2RAMP3CALCR | |
| SCHEMBL31031602 | 0.86 | F2 (0.59) | CXCR4MC4RAPLNRF2RAMP3 | |
| SCHEMBL29608128 | 0.86 | CXCR4 (0.57) | CXCR4MC4RAPLNRC5AR1 | |
| SCHEMBL29607774 | 0.86 | APLNR (0.54) | CXCR4MC4RAPLNRC5AR1 | |
| SCHEMBL31186830 | 0.85 | F2 (0.57) | CXCR4MC4RAPLNRF2RAMP3 | |
| SCHEMBL29801157 | 0.85 | APLNR (0.60) | APLNRC5AR1F2RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034913-B2 | Anti-angiogenic peptides and uses thereof | HEALTH RESEARCH, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20160051623-A1 | ANTI-ANGIOGENIC PEPTIDES AND USES THEREOF | HEALTH RESEARCH, INC. | 2016-02-25 | — | — | US | disclosed |
| US-20140309170-A1 | ANTI-ANGIOGENIC PEPTIDES AND USES THEREOF | HEALTH RESEARCH, INC. (US) | 2014-10-16 | — | — | US | disclosed |
| WO-2013019445-A2 | ANTI-ANGIOGENIC PEPTIDES AND USES THEREOF | HEALTH RESEARCH, INC. (US) | 2013-02-07 | — | — | WO | disclosed |