Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677076 | 0.89 | RORC (0.45) | RORCGAAALDH1A1LMNATP53 | |
| SCHEMBL14676262 | 0.84 | RORC (0.62) | RORCGAACYP26A1CYP26B1PTGS1 | |
| SCHEMBL14676263 | 0.84 | RORC (0.62) | RORCGAACYP26A1CYP26B1PTGS1 | |
| SCHEMBL14677460 | 0.81 | RORC (0.50) | RORCGAACYP26A1CYP26B1PTGS1 | |
| SCHEMBL14677417 | 0.79 | RORC (0.79) | RORCALDH1A1KMT2APSMB8PSMB5 | |
| SCHEMBL14676941 | 0.77 | GAA (0.41) | RORCGAACYP26A1CYP26B1PTGS1 | |
| SCHEMBL7997932 | 0.76 | CYP26A1 (0.48) | GAACYP26A1CYP26B1PTGS1AKR1C3 | |
| SCHEMBL14677062 | 0.75 | CYP26A1 (0.51) | RORCGAACYP26A1CYP26B1PTGS1 | |
| SCHEMBL14677114 | 0.74 | GAA (0.43) | RORCGAACYP26A1CYP26B1PTGS1 | |
| SCHEMBL14676010 | 0.72 | RORC (0.59) | RORCGAAALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736330-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013019682-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-02-07 | — | — | WO | disclosed |