Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.48 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979172 | 0.81 | GAA (0.51) | CYP26A1CYP26B1GAAPTGS1AKR1C3 | |
| SCHEMBL14676941 | 0.78 | GAA (0.41) | CYP26A1CYP26B1GAAPTGS1AKR1C3 | |
| SCHEMBL6543615 | 0.77 | CYP26A1 (0.53) | CYP26A1CYP26B1GAAPTGS1AKR1C3 | |
| SCHEMBL7428695 | 0.77 | CYP26A1 (0.45) | CYP26A1CYP26B1GAAPTGS1AKR1C3 | |
| SCHEMBL26355892 | 0.77 | S1PR1 (0.35) | CYP26A1CYP26B1S1PR1S1PR3LMNA | |
| SCHEMBL14677461 | 0.76 | RORC (0.47) | CYP26A1CYP26B1GAAPTGS1AKR1C3 | |
| SCHEMBL28784797 | 0.75 | LMNA (0.64) | GAAS1PR1S1PR3LMNATP53 | |
| SCHEMBL14677235 | 0.74 | CYP26A1 (0.50) | CYP26A1CYP26B1GAAPTGS1AKR1C3 | |
| SCHEMBL25764440 | 0.73 | MMP2 (0.46) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL7996062 | 0.73 | FLT3 (0.59) | GAAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |