Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.71 |
| ▸ | THRB | P10828 | 12/20 | 0.71 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.65 |
| ▸ | RARB | P10826 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14679132 | 0.93 | THRA (0.60) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL11715472 | 0.88 | THRA (0.73) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL13267849 | 0.86 | THRA (0.75) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL1577439 | 0.86 | HAO1 (0.79) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL8903148 | 0.86 | THRA (0.75) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL11435461 | 0.86 | THRA (0.75) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL10883866 | 0.86 | THRA (0.75) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL11427685 | 0.86 | THRA (0.75) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL15960542 | 0.84 | THRA (0.79) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL11715480 | 0.84 | THRA (0.73) | THRATHRBHAO1RARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367713-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |