Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 8/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 4/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178945 | 0.91 | SYK (0.55) | SYKALDH1A1ALOX15CTSKCTSL | |
| SCHEMBL2775895 | 0.91 | PPARA (0.57) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL29398102 | 0.91 | SYK (0.57) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL478289 | 0.91 | PPARA (0.57) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL1143898 | 0.91 | PPARA (0.57) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL19694832 | 0.90 | KYNU (0.56) | SYKALDH1A1ALOX15CTSKCTSL | |
| Water SCHEMBL29401166 | 0.90 | PPARA (0.56) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL19694834 | 0.90 | KYNU (0.56) | SYKALDH1A1ALOX15CTSKCTSL | |
| SCHEMBL4256075 | 0.90 | KYNU (0.56) | SYKALDH1A1ALOX15CTSKCTSL | |
| Water SCHEMBL2580712 | 0.90 | PPARA (0.56) | SYKCTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388144-B2 | Radiolabeled prostate specific membrane antigen inhibitors | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150078998-A1 | RADIOLABELED PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2015-03-19 | — | — | US | disclosed |
| US-8926944-B2 | Radiolabeled prostate specific membrane antigen inhibitors | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2015-01-06 | — | — | US | disclosed |
| US-20130034494-A1 | RADIOLABELED PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130034494-A1 | RADIOLABELED PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | KLK3, FOLH1, PSMA1 | SYK 4202/4885ALDH1A1 2469/4885ALOX15 4615/4885 |
| US-20150078998-A1 | RADIOLABELED PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | KLK3, FOLH1, PSMA2 | SYK 4309/4885ALDH1A1 1927/4885ALOX15 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.