Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 11/20 | 0.47 |
| ▸ | SYK | P43405 | 5/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14674189 | 0.91 | KARS1 (0.47) | KARS1SYKKDR | |
| SCHEMBL14680988 | 0.87 | GAA (0.44) | SYKKDR | |
| SCHEMBL2225653 | 0.87 | KARS1 (0.53) | KARS1SYKKDR | |
| SCHEMBL14673453 | 0.79 | KARS1 (0.61) | KARS1SYKKDRGSK3A | |
| SCHEMBL2228189 | 0.79 | KARS1 (0.55) | KARS1SYKKDRGSK3A | |
| SCHEMBL14674834 | 0.79 | GAA (0.44) | KDR | |
| SCHEMBL13136238 | 0.78 | KARS1 (0.47) | KARS1SYKKDRMAPK10 | |
| SCHEMBL13136173 | 0.78 | KARS1 (0.48) | KARS1SYKKDRMAPK10 | |
| SCHEMBL13136251 | 0.78 | KARS1 (0.60) | KARS1SYKKDR | |
| SCHEMBL2280792 | 0.77 | KARS1 (0.73) | KARS1SYKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962665-B2 | Thiazole and oxazole kinase inhibitors | AB SCIENCE (FR) | 2015-02-24 | — | — | US | disclosed |
| US-20130035331-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | AB SCIENCE (FR) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035331-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | SYK, LTK, MERTK | KARS1 1099/4885SYK 1/4885KDR 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.