Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.31 |
| ▸ | RELA | Q04206 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14684154 | 0.87 | CCNT1 (0.33) | CCNT1SYKDGAT1 | |
| SCHEMBL14680992 | 0.82 | KARS1 (0.47) | SLC2A1SYKDGAT1KDR | |
| SCHEMBL14673963 | 0.80 | FLT1 (0.39) | CCNT1RAB9ASYKSMN1; SMN2DGAT1 | |
| SCHEMBL2228275 | 0.78 | KDR (0.46) | CCNT1MEN1KMT2ASLC2A1PDE10A | |
| SCHEMBL2226110 | 0.76 | SLC2A1 (0.44) | RAB9AMEN1KMT2ASLC2A1NPC1 | |
| SCHEMBL2229276 | 0.71 | KDR (0.46) | RAB9AMEN1KMT2ASLC2A1NPC1 | |
| SCHEMBL2352796 | 0.69 | GRM5 (0.41) | CCNT1RAB9AMEN1KMT2ASLC2A1 | |
| SCHEMBL14673765 | 0.69 | ABL1 (0.39) | CCNT1F10CYP3A4 | |
| SCHEMBL2228280 | 0.68 | MAPT (0.34) | CCNT1RAB9AMEN1KMT2ASLC2A1 | |
| SCHEMBL4898748 | 0.68 | SLC2A1 (0.50) | RAB9AMEN1KMT2ASLC2A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962665-B2 | Thiazole and oxazole kinase inhibitors | AB SCIENCE (FR) | 2015-02-24 | — | — | US | disclosed |
| US-8962665-B2 | Thiazole and oxazole kinase inhibitors | AB SCIENCE (FR) | 2015-02-24 | — | — | US | disclosed |
| US-20130035331-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | AB SCIENCE (FR) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035331-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | SYK, LTK, MERTK | CCNT1 2633/4885F10 3957/4885RAB9A 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.