SCHEMBL14683468

SCHEMBL14683468

COCCOCC(=O)NCCOCCOCC(=O)NCCC[C@H](C)C(C)=O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ GLP1R P43220 8/20 0.38
▸ HPGD P15428 4/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ NAMPT P43490 1/20 0.34
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14683460 0.96 GLP1R (0.41) TSHRMEN1KMT2AGLP1RHPGD
SCHEMBL14683581 0.89 ALDH1A1 (0.40) TSHRMEN1KMT2AGLP1RALDH1A1
SCHEMBL12118613 0.86 GLP1R (0.42) TSHRMEN1KMT2AGLP1RKDM4E
SCHEMBL71147 0.85 GLP1R (0.46) TSHRMEN1KMT2AGLP1REPHX2
SCHEMBL71906 0.85 MEN1 (0.45) TSHRMEN1KMT2AGLP1REPHX2
SCHEMBL14683467 0.85 GLP1R (0.44) TSHRMEN1KMT2AGLP1RALDH1A1
SCHEMBL71315 0.85 GLP1R (0.46) TSHRMEN1KMT2AGLP1REPHX2
SCHEMBL14683527 0.85 GLP1R (0.44) TSHRMEN1KMT2AGLP1RALDH1A1
SCHEMBL12118741 0.84 GLP1R (0.41) TSHRMEN1KMT2AGLP1R
SCHEMBL13805652 0.83 GLP1R (0.49) TSHRMEN1KMT2AGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GIPR, IAPP TSHR 197/4885MEN1 858/4885KMT2A 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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